Article
Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa.
Life sciences - 1 Jan 1997
Hinney A, Barth N, Ziegler A, von Prittwitz S, Hamann A, Hennighausen K, Pirke K M, Heils A, Rosenkranz K, Roth H, Coners H, Mayer H, Herzog W, Siegfried A, Lehmkuhl G, Poustka F, Schmidt M H, Schäfer H, Grzeschik K H, Lesch K P, Lentes K U, Remschmidt H, Hebebrand J
Abstract excerpt
Several lines of evidence implicate a role for the serotonergic system in body weight regulation and eating disorders. The magnitude and duration of postsynaptic responses to serotonin (5-HT) is directed by the transport into and release from the presynaptic neuron. Recently, a common polymorphism of a repetitive element in the region of the serotonin transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR)...
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