Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serotonin receptor 2A -1438G/A promoter polymorphism in relation to obesity and response to sibutramine.

Genetic testing and molecular biomarkers - 1 Feb 2012

Papazoglou Dimitrios, Restas Emmanouel, Papanas Nikolaos, Papatheodorou Konstantinos, Babouris Christos, Glaros Dimitrios, Antonoglou Christos, Maltezos Efstratios

Abstract excerpt

AIMS: Serotonin has been related to appetite and body weight control. The aim of this study was to investigate a possible association of the -1438 /A promoter polymorphism of the serotonin 2A receptor (5HT2AR) gene with obesity-related variables and response to sibutramine. PATIENTS/METHODS: We examined the potential impact of this polymorphism on obesity and related metabolic traits in a cohort of 234...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Composition
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Weight

Share to Greece

Share to Obesity

Share to Overweight

Share to Receptor, Serotonin, 5-HT2A

Share to Weight Loss

Source

Identifiers

PMID: 21977970
DOI: 10.1089/gtmb.2011.0133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serotonin receptor 2A -1438G/A promoter polymorphism in relation to obesity and response to sibutramine.PMID 21977970Read ↗

Impact of the -1438G>a polymorphism in the serotonin 2A receptor gene on anthropometric profile and obesity risk: a case-control study in a Spanish Mediterranean population.Semantic proximity Read ↗

No evidence of association between the serotonin 2A receptor--1438G/A promoter polymorphism and childhood obesity in a Spanish population: A case-parent study and a matched case-control study.Semantic proximity Read ↗

Genetic polymorphism c.1438A>G of the 5-HT(2A) receptor is associated with abdominal obesity in Chinese Northern Han population.Semantic proximity Read ↗

5-HT2A receptor gene polymorphism and eating disorders.Semantic proximity Read ↗

5-HT2A receptor gene promoter polymorphism in relation to abdominal obesity and cortisol.Semantic proximity Read ↗

Increased abdominal obesity in subjects with a mutation in the 5-HT(2A) receptor gene promoter.Semantic proximity Read ↗

A controlled pharmacogenetic trial of sibutramine on weight loss and body composition in obese or overweight adults.Semantic proximity Read ↗

Further exploration of the possible influence of polymorphisms in HTR2C and 5HTT on body weight.Semantic proximity Read ↗

Prediction of successful weight reduction under sibutramine therapy through genotyping of the G-protein beta3 subunit gene (GNB3) C825T polymorphism.Semantic proximity Read ↗

LEPR, ADBR3, IRS-1 and 5-HTT genes polymorphisms do not associate with obesity.Semantic proximity Read ↗

Effect of the G-protein β3 subunit 825T allele on the change of body adiposity in obese female.Semantic proximity Read ↗

Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.