Article
Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels.
Physiological genomics - 7 Jul 2010
Zhang Y, Smith E M, Baye T M, Eckert J V, Abraham L J, Moses E K, Kissebah A H, Martin L J, Olivier M
Abstract excerpt
Neurotransmitters such as serotonin (5-hydroxytryptamine, 5-HT) work closely with leptin and insulin to fine-tune the metabolic and neuroendocrine responses to dietary intake. Losing the sensitivity to excess food intake can lead to obesity, diabetes, and a multitude of behavioral disorders. It is largely unclear how different serotonin receptor subtypes respond to and integrate metabolic signals and which...
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