Article
Genetic polymorphism c.1438A>G of the 5-HT(2A) receptor is associated with abdominal obesity in Chinese Northern Han population.
Molecular biology reports - 1 Jan 2009
Ying Su, Liu Xiao-Min, Sun Yan-Ming, Pan Shang-Ha
Abstract excerpt
OBJECTIVE: We examined the potential impact of the 5-hydroxytryptamine 2A receptor (5-HT(2A)R) c.1438A>G promoter polymorphism on obesity and estimates of insulin, glucose as well as lipid metabolism. METHODS: The genotypes and allelic frequencies of the 5-HT(2A)R c.1438A>G were examined with polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) in 210 patients with overweight/obesity...
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