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Article

ALK rearrangements in EBUS-derived transbronchial needle aspiration cytology in lung cancer.

Cytopathology : official journal of the British Society for Clinical Cytology - 1 Dec 2013

Neat M J, Foot N J, Hicks A, Breen R, Wilkins B, McLean E, Santis G

Abstract excerpt

OBJECTIVES: Patients with non-small cell lung cancer (NSCLC) positive for anaplastic lymphoma kinase (ALK) gene rearrangements may be treated successfully with the ALK inhibitor crizotinib. ALK copy-number abnormalities have also been described. In this study, we evaluated the suitability of fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) to determine ALK status in endobronchial...

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Topics

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Share to Adenocarcinoma
Share to Anaplastic Lymphoma Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bronchoscopy

Share to Endoscopic Ultrasound-Guided Fine Needle Aspiration

Share to In Situ Hybridization, Fluorescence

Share to Lung Neoplasms

Share to Lymphatic Metastasis

Share to Receptor Protein-Tyrosine Kinases

Source

Identifiers

PMID: 23551582
DOI: 10.1111/cyt.12060

Genes

ALK
KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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