Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2009

Rodig Scott J, Mino-Kenudson Mari, Dacic Sanja, Yeap Beow Y, Shaw Alice, Barletta Justine A, Stubbs Hannah, Law Kenny, Lindeman Neal, Mark Eugene, Janne Pasi A, Lynch Thomas, Johnson Bruce E, Iafrate A John, Chirieac Lucian R

Abstract excerpt

PURPOSE: The anaplastic large cell kinase gene (ALK) is rearranged in approximately 5% of lung adenocarcinomas within the Asian population. We evaluated the incidence and the characteristics of ALK-rearranged lung adenocarcinomas within the western population and the optimal diagnostic modality t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Anaplastic Lymphoma Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Cytogenetic Analysis

Share to Germ-Line Mutation

Share to Lung Neoplasms

Share to Protein-Tyrosine Kinases

Share to Receptor Protein-Tyrosine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 19671850
DOI: 10.1158/1078-0432.CCR-09-0802
PMCID: PMC2865649

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19671850-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population.PMID 19671850Read ↗

Anaplastic lymphoma kinase (ALK) mutations in patients with adenocarcinoma of the lung.Semantic proximity Read ↗

The molecular detection and clinical significance of ALK rearrangement in selected advanced non-small cell lung cancer: ALK expression provides insights into ALK targeted therapy.Semantic proximity Read ↗

Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomasSemantic proximity Read ↗

Combined use of ALK immunohistochemistry and FISH for optimal detection of ALK-rearranged lung adenocarcinomas.Semantic proximity Read ↗

ALK immunohistochemistry is highly sensitive and specific for the detection of ALK translocated lung adenocarcinomas: lessons from an audit of lung cancer molecular testing.Semantic proximity Read ↗

Prevalence and clinicopathological characteristics of ALK fusion subtypes in lung adenocarcinomas from Chinese populations.Semantic proximity Read ↗

ALK alterations and inhibition in lung cancer.Semantic proximity Read ↗

Anaplastic lymphoma kinase rearrangements in non-small-cell lung cancer: novel applications in diagnostics and treatment.Semantic proximity Read ↗

ALK in lung cancer: past, present, and future.Semantic proximity Read ↗

Clinicopathologic characteristics of ALK rearrangements in primary lung adenocarcinoma with identified EGFR and KRAS status.Semantic proximity Read ↗

Fluorescence In Situ Hybridization and Immunohistochemistry as Diagnostic Methods for ALK Positive Non-Small Cell Lung Cancer PatientsSemantic proximity Read ↗

Clinical Characteristics and Outcomes of Patients with Primary Lung Adenocarcinoma Harboring ALK Rearrangements Detected by FISH, IHC, and RT-PCRSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.