Article
Next-Generation Sequencing for Antenatal Prediction of KEL1 Blood Group Status.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Rieneck Klaus, Clausen Frederik Banch, Dziegiel Morten Hanefeld
Abstract excerpt
The KEL1 antigen can give rise to immunization of KEL2 mothers. Maternal antibodies can be transferred to the fetus and destroy fetal red blood cells and their stem cell precursors and give rise to serious fetal disease. It is important to be able to predict the fetal KEL status in order to intervene in those pregnancies where the fetus is at risk, and to ascertain when the fetus is not at risk. Technically it...
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