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Article

Association of TRPC1 gene polymorphisms with type 2 diabetes and diabetic nephropathy in Han Chinese population.

Endocrine research - 1 Jan 2013

Chen Kelin, Jin Xuehua, Li Qiang, Wang Wei, Wang Yan, Zhang Jinchao

Abstract excerpt

The recent genome-wide association studies reveal that chromosome 3q resides within the linkage region for diabetic nephropathy (DN) in type 1 and type 2 diabetes mellitus (T1D and T2D). The TRPC1 gene is on chromosome 3q22-24, and it has been demonstrated that TRPC1 expression is reduced in the kidney of diabetic animal models. Genetic association of TRPC1 polymorphism with T1D and DN has been reported in...

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Identifiers

PMID: 23544998
DOI: 10.3109/07435800.2012.681824
PMCID: PMC3619450

Genes

TRPC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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