Article
Association of genetic variants at 3q22 with nephropathy in patients with type 1 diabetes mellitus.
American journal of human genetics - 1 Jan 2009
He Bing, Osterholm Anne-May, Hoverfält Anna, Forsblom Carol, Hjörleifsdóttir Eyrún Edda, Nilsson Ann-Sofie, Parkkonen Maikki, Pitkäniemi Janne, Hreidarsson Astrádur, Sarti Cinzia, McKnight Amy Jayne, Maxwell A Peter, Tuomilehto Jaakko, Groop Per-Henrik, Tryggvason Karl
Abstract excerpt
Diabetic nephropathy (DN) is the primary cause of morbidity and mortality in patients with type 1 diabetes mellitus (T1DM) and affects about 30% of these patients. We have previously localized a DN locus on chromosome 3q with suggestive linkage in Finnish individuals. Linkage to this region has a...
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