Article
A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes.
Diabetes care - 1 Apr 2010
Ohshige Toshihiko, Tanaka Yasushi, Araki Shin-ichi, Babazono Tetsuya, Toyoda Masao, Umezono Tomoya, Watada Hirotaka, Suzuki Daisuke, Iwamoto Yasuhiko, Kawamori Ryuzo, Nakamura Yusuke, Maeda Shiro
Abstract excerpt
OBJECTIVE: Genetic factors have been considered to contribute to the development and progression of diabetic nephropathy. The KCNQ1 gene (potassium voltage-gated channel, KQT-like subfamily, member 1) was originally identified as a strong susceptibility gene for type 2 diabetes in two Japanese genome-wide association studies. In this study, we examined the association of single nucleotide polymorphisms (SNPs)...
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