Article
Multigenic combination of estrogen-related genes is associated with age at natural menopause in a Spanish population.
Menopause international - 1 Dec 2009
Mendoza Nicolás, Sánchez-Borrego Rafael, Galiano Daniela, Salamanca Alberto, Mozas Juan, Quereda Francisco, Vázquez Francisco, Martínez-Astorquiza Txantón, Moron Francisco
Abstract excerpt
OBJECTIVE: Age at natural menopause (ANM) can be considered a complex parameter that depends on the interaction of multiple factors. In the present study, the role of interaction between genetic variants within estrogen synthesis and signalling pathways in the ANM in Spanish women is studied. MATERIAL AND METHODS: Nine single nucleotide polymorphisms (SNPs) located at different candidate genes related to the...
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