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Article

YAP-mediated regulation of the chondrogenic phenotype in response to matrix elasticity.

Journal of molecular histology - 1 Oct 2013

Zhong Weiliang, Li Ying, Li Linan, Zhang Weiguo, Wang Shouyu, Zheng Xifu

Abstract excerpt

Matrix elasticity exerts considerable influence on the phenotype of terminally differentiated chondrocytes via physical cues. The Yes-associated protein (YAP) transcription co-activator is recognized as a key mediator that may be involved in the nuclear transduction of physical cues controlling cellular behavior and function. However, whether substrate elasticity in the regulation of the chondrocyte phenotype is...

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Source

Identifiers

PMID: 23543231
DOI: 10.1007/s10735-013-9502-y

Genes

LATS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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