Article
Intramolecular regulation of presynaptic scaffold protein SYD-2/liprin-α.
Molecular and cellular neurosciences - 1 Sept 2013
Chia Poh Hui, Patel Maulik R, Wagner Oliver I, Klopfenstein Dieter R, Shen Kang
Abstract excerpt
SYD-2/liprin-α is a multi-domain protein that associates with and recruits multiple active zone molecules to form presynaptic specializations. Given SYD-2's critical role in synapse formation, its synaptogenic ability is likely tightly regulated. However, mechanisms that regulate SYD-2 function are poorly understood. In this study, we provide evidence that SYD-2's function may be regulated by interactions between...
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