Article
A scaffold attachment factor PHM-2 regulates synaptic transmission through SLO-2 potassium channel in C. elegans.
PLoS genetics - 1 Mar 2026
Niu Longgang, Murugasen Karthika, Hanggodo Shannon, Ferdousy Sakia, Zhu Lishuang, Chen Bojun
Abstract excerpt
Scaffold attachment factor B (SAFB) proteins are evolutionarily conserved DNA/RNA binding proteins that are involved in multiple processes of gene expression. These proteins are broadly expressed with particular high expression observed in the nervous system. However, their physiological roles in neurons are largely unclear. Here we show that PHM-2, the sole SAFB ortholog in C. elegans, regulates synaptic...
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