Article
Heritable remodeling of yeast multicellularity by an environmentally responsive prion.
Cell - 28 Mar 2013
Holmes Daniel L, Lancaster Alex K, Lindquist Susan, Halfmann Randal
Abstract excerpt
Prion proteins undergo self-sustaining conformational conversions that heritably alter their activities. Many of these proteins operate at pivotal positions in determining how genotype is translated into phenotype. But the breadth of prion influences on biology and their evolutionary significance...
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