Article
Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.
Cell - 5 Apr 2018
Ding Li, Bailey Matthew H, Porta-Pardo Eduard, Thorsson Vesteinn, Colaprico Antonio, Bertrand Denis, Gibbs David L, Weerasinghe Amila, Huang Kuan-Lin, Tokheim Collin, Cortés-Ciriano Isidro, Jayasinghe Reyka, Chen Feng, Yu Lihua, Sun Sam, Olsen Catharina, Kim Jaegil, Taylor Alison M, Cherniack Andrew D, Akbani Rehan, Suphavilai Chayaporn, Nagarajan Niranjan, Stuart Joshua M, Mills Gordon B, Wyczalkowski Matthew A, Vincent Benjamin G, Hutter Carolyn M, Zenklusen Jean Claude, Hoadley Katherine A, Wendl Michael C, Shmulevich Llya, Lazar Alexander J, Wheeler David A, Getz Gad
Abstract excerpt
The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of diverse genomic alterations underlying human cancers. At this historic junction marking the completion of genomic characterization of over 11,000 tumors from 33 cancer types, we present our current understanding of the molecular processes governing oncogenesis. We illustrate our insights into cancer through synthesis of the findings of...
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