Article
Association between MIF gene polymorphisms and carotid artery atherosclerosis.
Biochemical and biophysical research communications - 31 May 2013
Lan Min-Yu, Chang Yung-Yee, Chen Wei-Hsi, Tseng Yu-Lung, Lin Hung-Sheng, Lai Shung-Lon, Liu Jia-Shou
Abstract excerpt
Atherosclerosis is a chronic inflammatory disorder. Macrophage migration inhibitory factor (MIF) is a potent cytokine that plays an important role in the regulation of immune responses. Polymorphisms including five- to eight-repeat CATT variants ((CATT)(5-8)) and G-173C in the promoter region of the MIF gene are associated with altered levels of MIF gene transcription. The purpose of the study is to investigate...
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