Article
MADD-4 is a secreted cue required for midline-oriented guidance in Caenorhabditis elegans.
Developmental cell - 18 Oct 2011
Seetharaman Ashwin, Selman Guillermo, Puckrin Rachel, Barbier Louis, Wong Eric, D'Souza Serena A, Roy Peter J
Abstract excerpt
The netrins and slits are two families of widely conserved cues that guide axons and cells along the dorsal-ventral (D-V) axis of animals. These cues typically emanate from the dorsal or ventral midlines and provide spatial information to migrating cells by forming gradients along the D-V axis. Some cell types, however, extend processes to both the dorsal and ventral midlines, suggesting the existence of...
Topics
- ADAMTS Proteins
- Animals
- Animals, Genetically Modified
- Axons
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Adhesion Molecules
- Cell Movement
- Cues
- Extracellular Matrix Proteins
- Gene Expression Regulation, Developmental
- Guanine Nucleotide Exchange Factors