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Association between Alzheimer's disease genes and trajectories of cognitive function decline in Han Chinese in Taiwan.

Aging - 2 Jul 2021

Hsieh Tsung-Jen, Lee Wei-Ju, Liao Yi-Chu, Hsu Chih-Cheng, Fang Yao-Hwei, Chen Tzu-Yu, Lin Yung-Shuan, Chang I-Shou, Wang Shuu-Jiun, Hsiung Chao A, Fuh Jong-Ling

Abstract excerpt

Genetic background has been considered one of the important contributors to the rate of cognitive decline among patients with Alzheimer's disease (AD). We conducted a 4-year longitudinal follow-up study, recruited 255 AD and 44 mild cognitive impairment (MCI) patients, and used a data-driven trajectory analysis to examine the influence of selected AD risk genes on the age for and the rate of cognitive decline in...

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Identifiers

PMID: 34214049
DOI: 10.18632/aging.203204
PMCID: PMC8312434

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