Somatic Mutations of K-Ras and BRAF in Thai Colorectal Cancer and their Prognostic Value

Abstract excerpt

BACKGROUND: The study aimed to determine the incidence of K-ras and BRAF mutations in colorectal cancers (CRCs) in Thai patients and evaluate association with clinicopathological parameters including treatment outcomes in terms of event free survival (EFS). MATERIALS AND METHODS: Two-hundred colorectal cancer specimens were collected for studies of K-Ras codon 12, 13 and 61, and BRAF codon 600 by polymerase chain...

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