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Article

Association of Asthma Risk Alleles With Acute Respiratory Tract Infections and Wheezing Illnesses in Young Children.

The Journal of infectious diseases - 18 Oct 2023

Forsström Ville, Toivonen Laura, Homil Kiara, Waris Matti, Pedersen Casper-Emil T, Bønnelykke Klaus, Jartti Tuomas, Peltola Ville

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified several risk alleles for early childhood asthma, particularly in the 17q21 locus and in the cadherin-related family member 3 (CDHR3) gene. Contribution of these alleles to the risk of acute respiratory tract infections (ARI) in early childhood is unclear. METHODS: We analyzed data from the STEPS birth-cohort study of unselected children and the VINKU and...

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Identifiers

PMID: 36967681
DOI: 10.1093/infdis/jiad075
PMCID: PMC10582910

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