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Article

A T-cell response to a liver-stage <i>Plasmodium</i> antigen is not boosted by repeated sporozoite immunizations

25 Mar 2013

Abstract excerpt

Development of an antimalarial subunit vaccine inducing protective cytotoxic T lymphocyte (CTL)-mediated immunity could pave the way for malaria eradication. Experimental immunization with sporozoites induces this type of protective response, but the extremely large number of proteins expressed by Plasmodium parasites has so far prohibited the identification of sufficient discrete T-cell antigens to develop...

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PMID: 23530242
DOI: 10.1073/pnas.1303834110

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A T-cell response to a liver-stage <i>Plasmodium</i> antigen is not boosted by repeated sporozoite immunizationsPMID 23530242Read ↗

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