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Article

Mutant tristetraprolin: a potent inhibitor of malignant glioma cell growth.

Journal of neuro-oncology - 1 Jun 2013

Suswam Esther A, Shacka John J, Walker Kiera, Lu Liang, Li Xuelin, Si Ying, Zhang Xiaowen, Zheng Lei, Nabors L Burt, Cao Heping, King Peter H

Abstract excerpt

Malignant gliomas rely on the production of certain critical growth factors including VEGF, interleukin (IL)-6 and IL-8, to fuel rapid tumor growth, angiogenesis, and treatment resistance. Post-transcriptional regulation through adenine and uridine-rich elements of the 3' untranslated region is one mechanism for upregulating these and other growth factors. In glioma cells, we have shown that the...

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Identifiers

PMID: 23525947
DOI: 10.1007/s11060-013-1112-8
PMCID: PMC3679321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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