Article
Inference with viral quasispecies diversity indices: clonal and NGS approaches.
Bioinformatics (Oxford, England) - 15 Apr 2014
Gregori Josep, Salicrú Miquel, Domingo Esteban, Sanchez Alex, Esteban Juan I, Rodríguez-Frías Francisco, Quer Josep
Abstract excerpt
Given the inherent dynamics of a viral quasispecies, we are often interested in the comparison of diversity indices of sequential samples of a patient, or in the comparison of diversity indices of virus in groups of patients in a treated versus control design. It is then important to make sure that the diversity measures from each sample may be compared with no bias and within a consistent statistical framework....
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