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Article

The use of imputed sibling genotypes in sibship-based association analysis: on modeling alternatives, power and model misspecification.

Behavior genetics - 1 May 2013

Minică Camelia C, Dolan Conor V, Hottenga Jouke-Jan, Willemsen Gonneke, Vink Jacqueline M, Boomsma Dorret I

Abstract excerpt

When phenotypic, but no genotypic data are available for relatives of participants in genetic association studies, previous research has shown that family-based imputed genotypes can boost the statistical power when included in such studies. Here, using simulations, we compared the performance of...

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PMID: 23519635
DOI: 10.1007/s10519-013-9590-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23519635-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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