Article
Imputation of missing single nucleotide polymorphism genotypes using a multivariate mixed model framework.
Journal of animal science - 1 Jul 2011
Calus M P L, Veerkamp R F, Mulder H A
Abstract excerpt
The objective of this paper was to investigate, for various scenarios at low and high marker density, the accuracy of imputing genotypes when using a multivariate mixed model framework using information from 2, 4, or 10 surrounding markers. This model predicts genotypes at a locus, using genotypes at nearby loci as correlated traits, and the additive genetic relationship matrix to use information from genotyped...
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