Article
From antiretroviral therapy access to provision of third line regimens: evidence of HIV Drug resistance mutations to first and second line regimens among Ugandan adults.
BMC research notes - 23 Dec 2016
Namakoola Ivan, Kasamba Ivan, Mayanja Billy N, Kazooba Patrick, Lutaakome Joseph, Lyagoba Fred, Kapaata Anne A, Kaleebu Pontiano, Munderi Paula
Abstract excerpt
BACKGROUND: HIV care programs in resource-limited settings have hitherto concentrated on antiretroviral therapy (ART) access, but HIV drug resistance is emerging. In a cross-sectional study of HIV-positive adults on ART for ≥6 months enrolled into a prospective cohort in Uganda, plasma HIV RNA was measured and genotyped if ≥1000 copies/ml. Identified Drug resistance mutations (DRMs) were interpreted using the...
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