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Article

Gallstone disease in Swedish twins is associated with the Gilbert variant of UGT1A1.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jul 2013

Marschall Hanns-Ulrich, Krawczyk Marcin, Grünhage Frank, Katsika Despina, Einarsson Curt, Lammert Frank

Abstract excerpt

BACKGROUND & AIMS: The Gilbert syndrome-associated functional TATA box variant UGT1A1*28 (A(TA)7TAA) was found to increase susceptibility to pigment gallstone formation in patients with haemolytic anaemia. Further studies in extensive cohorts demonstrated an increased risk of this variant for cholesterol gallstone disease (GD). We now investigated this polymorphism as a determinant of symptomatic GD in Swedish...

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Identifiers

PMID: 23517300
DOI: 10.1111/liv.12141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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