Article
Gilbert syndrome as a predisposing factor for cholelithiasis risk in the Greek adult population.
Genetic testing and molecular biomarkers - 1 Feb 2009
Tsezou Aspasia, Tzetis Maria, Giannatou Eirini, Spanos Ierotheos, Roma Eleutheria, Fretzayas Alexandros, Kanavakis Emmanuel, Kitsiou-Tzeli Sofia
Abstract excerpt
We investigated the hypothesis that coinheritance of the common A(TA)(n)TAA promoter mutation at the UGT1A1 locus associated with Gilbert syndrome is a risk factor for gallstone formation in a homogeneous adult population, by conducting a case-control study that included 198 adult patients with cholelithiasis and 152 healthy controls both of Greek origin. Three genotypes were found: 7/7 (17.8% in controls and...
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