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Article

Molecular genetic basis of Gilbert's syndrome.

Journal of gastroenterology and hepatology - 1 Oct 1999

Burchell B, Hume R

Abstract excerpt

Gilbert's syndrome, an hereditary, chronic, mild, unconjugated hyperbilirubinaemia resulting from impaired hepatic bilirubin clearance and otherwise normal liver function, is arguably the most common syndrome known in humans. Recent molecular genetic studies have determined that the clinical phenotype can be described by a dinucleotide polymorphism in the TATA box promoter of the bilirubin uridine...

Topics

Genotype
Gilbert Disease
Glucuronides
Glucuronosyltransferase
Heterozygote
Humans
Hyperbilirubinemia
Inactivation, Metabolic
Infant, Newborn
Jaundice, Neonatal
Male
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

TATA Box

Source

Identifiers

PMID: 10530490
DOI: 10.1046/j.1440-1746.1999.01984.x

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