Article
Thalassemia minor, the Gilbert mutation, and the risk of gallstones.
Haematologica - 1 Oct 2003
Borgna-Pignatti Caterina, Rigon Francesca, Merlo Luciano, Chakrok Roksana, Micciolo Rocco, Perseu Luciana, Galanello Renzo
Abstract excerpt
BACKGROUND AND OBJECTIVES: Gallstones are a frequent complication of hemolytic anemias. The association with the mutation of the A(TA)nTAA motif of the promoter of the bilirubin UDP-glucuronosyltransferase gene has also been reported to increase the risk of gallstones. We studied the prevalence of cholelithiasis in thalassemia minor and the role of the Gilbert mutation. DESIGN AND METHODS: A group of 143 women...
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