Article
EGFR mutational status in penile cancer.
Expert opinion on therapeutic targets - 1 May 2013
Di Lorenzo Giuseppe, Buonerba Carlo, Gaudioso Gabriella, Gigantino Vincenzo, Quarto Giuseppe, De Domenico Renato, Caraglia Michele, Di Trolio Rossella, Ascierto Paolo A, De Placido Sabino, Perdonà Sisto, Franco Renato
Abstract excerpt
OBJECTIVE: No substantial improvement in overall survival has been obtained over the past two decades in penile cancer (PC). Clinical data are available on the role of epidermal growth factor receptors (EGFR) inhibitors in PC but no EGFR mutational analysis has been conducted. RESEARCH DESIGN AND METHODS: We reviewed formalin-fixed, paraffin-embedded blocks of PC at the Pathology Department of the National Cancer...
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