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Article

Establishment and characterization of a penile cancer cell line, penl1, with a deleterious TP53 mutation as a paradigm of HPV-negative penile carcinogenesis.

Oncotarget - 9 Aug 2016

Chen Jieping, Yao Kai, Li Zaishang, Deng Chuangzhong, Wang Liangjiao, Yu Xingsu, Liang Peili, Xie Qiankun, Chen Peng, Qin Zike, Ye Yunlin, Liu Zhuowei, Zhou Fangjian, Zhang Zhenfeng, Han Hui

Abstract excerpt

PURPOSE: To establish penile cancer (PeCa) cell lines for the study of molecular mechanisms of carcinogenesis and testing therapeutic reagents. MATERIALS AND METHODS: We successfully established two PeCa cell lines from fresh tumor tissues from 21 cases. One cell line named Penl1 was isolated from a lymph node metastasis (LNM) of penile squamous cell carcinoma (PeSCC), usual type and comprehensively characterized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27351128
DOI: 10.18632/oncotarget.10098
PMCID: PMC5239507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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