Article
Biosynthesis of kalafungin in Streptomyces tanashiensis.
The Journal of antibiotics - 1 Apr 1990
Kakinuma S, Ikeda H, Omura S, Hopwood D A
Abstract excerpt
The mutants of Streptomyces tanashiensis strain Kala, which were specifically blocked in the synthesis of the benzoisochromanequinone antibiotic kalafungin, were isolated and classified into seven phenotypic classes on the basis of the antibiotic activity and cosynthetic properties. The polarity of cosynthetic reactions and the production of kalafungin by a converter strain showed that the seven mutant classes...
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