Article
Characterization of Discrete Phosphopantetheinyl Transferases in Streptomyces tsukubaensis L19 Unveils a Complicate Phosphopantetheinylation Network.
Scientific reports - 7 Apr 2016
Wang Yue-Yue, Zhang Xiao-Sheng, Luo Hong-Dou, Ren Ni-Ni, Jiang Xin-Hang, Jiang Hui, Li Yong-Quan
Abstract excerpt
Phosphopantetheinyl transferases (PPTases) play essential roles in both primary metabolisms and secondary metabolisms via post-translational modification of acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs). In this study, an industrial FK506 producing strain Streptomyces tsukubaensis L19, together with Streptomyces avermitilis, was identified to contain the highest number (five) of discrete...
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