Article
An essential RNA element resides in a central region of hepatitis E virus ORF2.
The Journal of general virology - 1 Jul 2013
Emerson Suzanne U, Nguyen Hanh T, Torian Udana, Mather Karly, Firth Andrew E
Abstract excerpt
Hepatitis E virus (genus Hepevirus, family Hepeviridae) is one of the most important causes of acute hepatitis in adults, particularly among pregnant women, throughout Asia and Africa where mortality rates can be 20-30 %. Hepatitis E virus has a single-stranded positive-sense RNA genome that contains three translated ORFs. The two 3' ORFs are translated from a subgenomic RNA. Functional RNA elements have been...
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