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Molecular biology and replication of hepatitis E virus

1 Jul 2012

Abstract excerpt

Hepatitis E virus (HEV), a single-stranded, positive-sense RNA virus, is responsible for acute hepatitis E epidemics in many developing countries, and the virus is also endemic in some industrialized countries. Hepatitis E is a recognized zoonotic disease, and several animal species, including pigs, are potential reservoirs for HEV. The genome of HEV contains three open reading frames (ORFs). ORF1 encodes the...

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PMID: 26038426
DOI: 10.1038/emi.2012.7

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