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Article

Paired ductal carcinoma in situ and invasive breast cancer lesions in the D-loop of the mitochondrial genome indicate a cancerization field effect.

BioMed research international - 1 Jan 2013

Maggrah Andrea, Robinson Kerry, Creed Jennifer, Wittock Roy, Gehman Ken, Gehman Teresa, Brown Helen, Harbottle Andrew, Froberg M Kent, Klein Daniel, Reguly Brian, Parr Ryan

Abstract excerpt

Alterations in the mitochondrial genome have been chronicled in most solid tumors, including breast cancer. The intent of this paper is to compare and document somatic mitochondrial D-loop mutations in paired samples of ductal carcinoma in situ (DCIS) and invasive breast cancer (IBC) indicating a potential breast ductal epithelial cancerization field effect. Paired samples of these histopathologies were...

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Identifiers

PMID: 23509716
DOI: 10.1155/2013/379438
PMCID: PMC3591154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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