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Article

Funny channel gene mutations associated with arrhythmias.

The Journal of physiology - 1 Sept 2013

DiFrancesco Dario

Abstract excerpt

Many diverse data support a role of the funny current (If) in pacemaking and heart rate control. Among them, clinically relevant applications have special impact, since they translate the concept of funny channel-based pacemaking into practical developments of potential therapeutic value. For example, the If role in pacemaking is the basis for a pharmacological approach to heart rate control. Ivabradine, a...

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Topics

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Share to Amino Acid Sequence
Share to Arrhythmias, Cardiac
Share to Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23507880
DOI: 10.1113/jphysiol.2013.253765
PMCID: PMC3779106

Genes

HCN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Funny channel gene mutations associated with arrhythmias.PMID 23507880Read ↗

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