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Article

HCN channels and heart rate.

Molecules (Basel, Switzerland) - 5 Apr 2012

Scicchitano Pietro, Carbonara Santa, Ricci Gabriella, Mandurino Cosimo, Locorotondo Manuela, Bulzis Gabriella, Gesualdo Michele, Zito Annapaola, Carbonara Rosa, Dentamaro Ilaria, Riccioni Graziano, Ciccone Marco Matteo

Abstract excerpt

Hyperpolarization and Cyclic Nucleotide (HCN) -gated channels represent the molecular correlates of the "funny" pacemaker current (I(f)), a current activated by hyperpolarization and considered able to influence the sinus node function in generating cardiac impulses. HCN channels are a family of six transmembrane domain, single pore-loop, hyperpolarization activated, non-selective cation channels. This channel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22481543
DOI: 10.3390/molecules17044225
PMCID: PMC6268830

Genes

HCN1
HCN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HCN channels and heart rate.PMID 22481543Read ↗

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