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Article

Updates on HCN Channels in the Heart: Function, Dysfunction and Pharmacology.

Current drug targets - 1 Jan 2015

Sartiani Laura, Romanelli Maria Novella, Mugelli Alessandro, Cerbai Elisabetta

Abstract excerpt

The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play an important role in the generation of pacemaker activity of cardiac sinoatrial node cells and immature cardiomyocytes. HCN channels are also present in adult atrial and ventricular cardiomyocytes, where the physiological...

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PMID: 26028050
DOI: 10.2174/1389450116666150531152047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26028050-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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