Article
A polymorphism of matrix Gla protein gene is associated with kidney stone in the Chinese Han population.
Gene - 15 Dec 2012
Lu Xiuli, Gao Bing, Liu Zehui, Tian Xiurong, Mao Xu, Emmanuel Newton, Zhu Qiwen, Xiao Chunling
Abstract excerpt
PURPOSE: Matrix Gla protein (MGP) is a molecular determinant regulating the extracellular matrix calcification. To further confirm whether the MGP genetic polymorphism was universally associated with the risk of kidney stone, we investigated the association of genetic polymorphisms of MGP with kidney stone in the Chinese Han population. MATERIALS AND METHODS: 728 subjects were recruited for the study. We firstly...
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