Article
Genetic features shared by Mycobacterium tuberculosis strains involved in microevolution events.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2013
Pérez-Lago Laura, Navarro Yurena, Herranz Marta, Bouza Emilio, García-de-Viedma Darío
Abstract excerpt
Microevolved Mycobacterium tuberculosis (MTB) clonal variants from a parental strain can emerge within a single patient infection and during transmission events. Genotypic rearrangements may involve functional changes conferring advantages to favor strain adaptation to the host. In the present study, we analyzed in depth some genotypic characteristics of a strain with a high tendency to microevolve that generated...
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