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Microevolution, reinfection and highly complex genomic diversity in patients with sequential isolates of Mycobacterium abscessus

28 Mar 2024

Abstract excerpt

Mycobacterium abscessus is an opportunistic, extensively drug-resistant non-tuberculous mycobacterium. Few genomic studies consider its diversity in persistent infections. Our aim was to characterize microevolution/reinfection events in persistent infections. Fifty-three sequential isolates from 14 patients were sequenced to determine SNV-based distances, assign resistance mutations and characterize plasmids....

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PMID: 38548737
DOI: 10.1038/s41467-024-46552-w

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