Article
Microevolution of Mycobacterium tuberculosis in a tuberculosis patient.
Journal of clinical microbiology - 1 Oct 2010
Al-Hajoj Sahal A M, Akkerman Onno, Parwati Ida, al-Gamdi Saad, Rahim Zeaur, van Soolingen Dick, van Ingen Jakko, Supply Philip, van der Zanden Adri G M
Abstract excerpt
Five Mycobacterium tuberculosis isolates were obtained from three body sites from a Dutch patient. The isolates displayed a single genotype by 24-locus MIRU-VNTR typing (except for a single locus not amplified from one isolate) but were differentiated by small variations in IS6110 fingerprints, spoligotypes, 6 hypervariable MIRU-VNTR loci, and/or DiversiLab profiles, revealing patterns of microevolution in a...
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