Article
Single-nucleotide polymorphisms in tumor necrosis factor receptor genes: definition of novel haplotypes and racial/ethnic differences.
Arthritis and rheumatism - 1 Aug 2002
Bridges S Louis, Jenq Grace, Moran Molly, Kuffner Tamara, Whitworth William C, McNicholl Janet
Abstract excerpt
OBJECTIVE: To characterize allele frequencies of known single-nucleotide polymorphisms (SNPs) in tumor necrosis factor receptor (TNFR) genes in African Americans with rheumatoid arthritis (RA), healthy African Americans, and healthy Caucasians. METHODS: One TNFRSF1B SNP (196 G/T) that influences susceptibility to familial RA in Caucasians and 3 SNPs in the 5' flanking region of the TNFRSF1A gene (-609G/T,...
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