Article
Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).
Metabolism: clinical and experimental - 1 Oct 2015
Wojczynski Mary K, Parnell Laurence D, Pollin Toni I, Lai Chao Q, Feitosa Mary F, O'Connell Jeff R, Frazier-Wood Alexis C, Gibson Quince, Aslibekyan Stella, Ryan Kathy A, Province Michael A, Tiwari Hemant K, Ordovas Jose M, Shuldiner Alan R, Arnett Donna K, Borecki Ingrid B
Abstract excerpt
OBJECTIVE: The triglyceride (TG) response to a high-fat meal (postprandial lipemia, PPL) affects cardiovascular disease risk and is influenced by genes and environment. Genes involved in lipid metabolism have dominated genetic studies of PPL TG response. We sought to elucidate common genetic variants through a genome-wide association (GWA) study in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)....
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