Article
Lipid-Glycoadjuvant@AuNPs Inhibits Tumor Gowth and Regulates Tumor Microenvironments by Tumor-Specific CTL-Ferived IFNγ
2021-07-29
Abstract excerpt
Inducing tumor-specific T cell responses and regulating suppressive tumor microenvironments have been a challenge for effective tumor therapy. CpG (ODN), the Toll-like receptor 9 agonist, has been widely used as adjuvants of cancer vaccines to induce T cell responses. However, clinical benefits of CpG based tumor vaccine were limited primarily due to the poor targeting to lymph nodes. Here we developed a lipid-gly...
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Identifiers and source
- Literature Corpus work
- 099f7547-27a0-56aa-879c-c2fa251eb5f3
- DOI
- 10.21203/rs.3.rs-746366/v1
