Article
Prevalence of HOXB13 mutation in a population of Ashkenazi Jewish men treated for prostate cancer.
Familial cancer - 1 Dec 2013
Alanee Shaheen, Shah Sohela, Vijai Joseph, Schrader Kasmintan, Hamilton Robert, Rau-Murthy Rohini, Sarrel Kara, Manschreck Christopher, Eastham James, Offit Kenneth
Abstract excerpt
We performed a retrospective analysis of germline DNA samples from Ashkenazi Jewish men and a comparison group of non-Ashkenazi men treated for prostate cancer at our institution to determine the prevalence of HOXB13 G84E mutation in prostate cancer patients of Ashkenazi Jewish heritage, an ethnic group common to the New York City area. Patients were genotyped for G84E using a TaqMan assay (Applied Biosystems)....
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