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Article

The impact of 3'UTR variants on differential expression of candidate cancer susceptibility genes.

PloS one - 1 Jan 2013

Skeeles Laura E, Fleming Jessica L, Mahler Kimberly L, Toland Amanda Ewart

Abstract excerpt

Variants in regulatory regions are predicted to play an important role in disease susceptibility of common diseases. Polymorphisms mapping to microRNA (miRNA) binding sites have been shown to disrupt the ability of miRNAs to target genes resulting in differential mRNA and protein expression. Skin tumor susceptibility 5 (Skts5) was identified as a locus conferring susceptibility to chemically-induced skin cancer...

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Identifiers

PMID: 23472213
DOI: 10.1371/journal.pone.0058609
PMCID: PMC3589377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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